« Previous
Journal of Tissue Viability
Volume 19, Issue 2
, Pages 77-83
, May 2010
Candidate biomarkers for deep tissue damage from molecular biological and biochemical aspects
References
- Pressure-related deep tissue injury under intact skin and current pressure ulcer staging systems. Adv Skin Wound Care. 2005;18:35–42
- National pressure ulcer advisory panel's updated pressure ulcer staging system. Urol Nurs. 2007;27:144–150
- . Deep tissue injury. Wounds. 2003;15:380
- Ultrasonographic evaluation of an unusual peri-anal induration: a possible case of deep tissue injury. J Wound Care. 2007;16:365–367
- Ultrasound assessment of deep tissue injury in pressure ulcers: possible prediction of pressure ulcer progression. Plast Reconstr Surg. 2009;124:540–550
- . Is obesity a risk factor for deep tissue injury in patients with spinal cord injury?. J Biomech. 2008;41:3322–3333
- . Are all pressure ulcers the result of deep tissue injury? A review of the literature. Ostomy Wound Manage. 2007;53:34–38
- . The etiology of pressure ulcers: skin deep or muscle bound?. Arch Phys Med Rehabil. 2003;84:616–619
- . Deep tissue injury: how deep is our understanding?. Arch Phys Med Rehabil. 2008;89:1410–1413
- . Role of ischemia and deformation in the onset of compression-induced deep tissue injury: MRI-based studies in a rat model. J Appl Phys. 2007;102:2002–2011
- . Ischemia-reperfusion injury in chronic pressure ulcer formation: a skin model in the rat. Wound Repair Regen. 2000;8:68–76
- . Lymphatic clearance during compressive loading. Lymphology. 1981;14:161–166
- . Relationship between oxidative stress and HIF-1 alpha mRNA during sustained hypoxia in humans. Free Radic Biol Med. 2009;46:321–326
- . Electron transfer and oxidative stress as key factors in the design of drugs selectively active in hypoxia. Curr Med Chem. 2001;8:739–761
- . Sitting can cause ischaemia in the subcutaneous tissue of the buttocks, which implicates multilayer tissue damage in the development of pressure ulcers. Scand J Plast Reconstr Surg Hand Surg. 2009;43:82–89
- . Temporal differences in the influence of ischemic factors and deformation on the metabolism of engineered skeletal muscle. J Appl Phys. 2007;103:464–473
- . The relative contributions of compression and hypoxia to development of muscle tissue damage: an in vitro study. Ann Biomed Eng. 2007;35:273–284
- . Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A. 1995;92:5510–5514
- . Hypoxia-inducible factor 1-alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations. Proc Natl Acad Sci U S A. 2000;97:4748–4753
- HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science. 2001;292:464–468
- Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel–Lindau tumor suppressor protein. J Biol Chem. 2000;275:25733–25741
- Targeting of HIF-alpha to the von Hippel–Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science. 2001;292:468–472
- . Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol. 2006;70:1469–1480
- . HIF-1 and human disease: one highly involved factor. Genes Dev. 2000;14:1983–1991
- Sari Y. Hypoxia is involved in deep tissue injury formation in a rat model. In: Masters thesis, The University of Tokyo Graduate School of Medicine; 2009.
- . Pressure-induced ischemic wound healing with bacterial inoculation in the rat. Wounds. 2005;17:157–168
- Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice. Proc Natl Acad Sci U S A. 2008;105:19426–19431
- . Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax. Biochem Biophys Res Commun. 2003;309:222–231
- . FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2. Mol Cell. 2007;28:941–953
- HIF1 transcription factor regulates laminin-332 expression and keratinocyte migration. J Cell Sci. 2008;121:2992–3001
- . Erythropoietin receptors in endometrial carcinoma as related to HIF1α and VEGF expression. In Vivo. 2009;23:699–703
- . Multiple molecular forms of creatine kinases. Ann N Y Acad Sci. 1968;151:616–626
- . Theoretical analysis of creatine kinase isozyme patterns in various human tissues and myopathic skeletal muscles. Tokushima J Exp Med. 1974;21:75–78
- . Effects of physical activity on creatine phosphokinase and the isoenzyme creatine kinase-MB. Ann Emerg Med. 1995;25:520–524
- . A serum isozyme study in muscular dystrophy. Particular reference to creatine kinase, aspartate aminotransferase, and lactic acid dehydrogenase isozymes. Arch Neurol. 1973;29:343–345
- . Plasma creatine kinase isozyme electrophoretic pattern of long-term vitamin E-deficient rats. Int J Vitam Nutr Res. 1983;53:138–142
- . Pressure sores: a biochemical test for early detection of tissue damage. Arch Phys Med Rehabil. 1988;69:668–671
- Changes in serum and exudate creatine phosphokinase concentrations as an indicator of deep tissue injury: a pilot study. Int Wound J. 2008;5:674–680
- . Updated staging system: pressure ulcer stages revised by NPUAP. http://www.npuap.org/pr2.htm2007;[accessed 6.10.09]
- . Pressure sores: classification and management. Clin Orthop Relat Res. 1975;112:89–100
- Muscle apoptosis is induced in pressure-induced deep tissue injury. J Appl Phys. 2009;doi:10.1152/japplphysiol.90897.2008
PII: S0965-206X(09)00050-3
doi: 10.1016/j.jtv.2009.10.004
« Previous
Journal of Tissue Viability
Volume 19, Issue 2
, Pages 77-83
, May 2010
