Journal of Tissue Viability
Volume 21, Issue 1 , Pages 13-16 , February 2012

The value of frozen section biopsy in diagnosing necrotizing fasciitis: Proposal of a new grading system

  • Sylvia A. Stegeman

      Affiliations

    • Department of Surgery, Leiden University Medical Centre, P.O. box 9600, 2300 RC Leiden, The Netherlands
    • Corresponding Author InformationCorresponding author.
    • ,
  • Irma Nijhuis

      Affiliations

    • Department of Anaesthesiology, St Antonius Hospital, P.O. box 2500, 3430 EM Nieuwegein, The Netherlands
    • ,
  • A.M. (Gijs) van Leeuwen

      Affiliations

    • Department of Pathology, Rijnland Hospital, P.O. box 4220, 2350 CC Leiderdorp, The Netherlands
    • ,
  • Bert A. Bonsing

      Affiliations

    • Department of Surgery, Leiden University Medical Centre, P.O. box 9600, 2300 RC Leiden, The Netherlands
    • ,
  • Pascal Steenvoorde

      Affiliations

    • Department of Surgery, Medical Spectrum Twente, P.O. box 50 000, 7500 KA Enschede, The Netherlands

References 

  1. Wong CH, Wang YS. The diagnosis of necrotizing fasciitis. Curr Opin Infect Dis. 2005 April;18(2):101–106
  2. Wong CH, Chang HC, Pasupathy S, Khin LW, Tan JL, Low CO. Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality. J Bone Jt Surg Am. 2003 August;85-A(8):1454–1460
  3. Elliott DC, Kufera JA, Myers RA. Necrotizing soft tissue infections. Risk factors for mortality and strategies for management. Ann Surg. 1996 November;224(5):672–683
  4. Green RJ, Dafoe DC, Raffin TA. Necrotizing fasciitis. Chest. 1996 July;110(1):219–229
  5. McHenry CR, Piotrowski JJ, Petrinic D, Malangoni MA. Determinants of mortality for necrotizing soft-tissue infections. Ann Surg. 1995 May;221(5):558–563
  6. Meleney FL. Hemolytic streptococcus gangrene. Arch Surg. 1924;9:317–364
  7. Patino JF, Castro D. Necrotizing lesions of soft tissues: a review. World J Surg. 1991 March;15(2):235–239
  8. Anaya DA, Dellinger EP. Necrotizing soft-tissue infection: diagnosis and management. Clin Infect Dis. 2007 March 1;44(5):705–710
  9. Stamenkovic I, Lew PD. Early recognition of potentially fatal necrotizing fasciitis. The use of frozen-section biopsy. N Engl J Med. 1984 June 28;310(26):1689–1693
  10. Majeski J, Majeski E. Necrotizing fasciitis: improved survival with early recognition by tissue biopsy and aggressive surgical treatment. South Med J. 1997 November;90(11):1065–1068

PII: S0965-206X(11)00051-9

doi: 10.1016/j.jtv.2011.10.002

Journal of Tissue Viability
Volume 21, Issue 1 , Pages 13-16 , February 2012

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